Orangeburg County Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $1,096 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Orangeburg County Vacation

Reserve a vacation package to Orangeburg County and make planning your getaway quick and easy. With all the logistics organized before you leave, you can focus on enjoying every second in this interesting destination. With so much to do and see on a trip to Orangeburg County, it can be difficult to know where to start. Kick off your journey in Santee at Santee State Park and Santee Cooper Country Club — two much-loved attractions here. Another great city worth adding to your itinerary is Orangeburg. Be sure not to miss Edisto Memorial Gardens and Smith-Hammond-Middleton Memorial Centre. Whether you plan to travel for a couple of days or a couple of weeks, Expedia are here to help you customize your next Orangeburg County vacation.

Top Orangeburg County Vacation Deals

Price found within the past 48 hours. Click for updated prices.
The Francis Marion Hotel
Planters Inn
The Ryder Hotel
The Nicholas
Indigo Inn

Orangeburg County Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is CA $111 per night from Apr 13 to Apr 14
CA $111
CA $123 total
Apr 13 - Apr 14
includes taxes & fees
7.8/10 Good! (1,443 reviews)
Clean room nice staff

Reviewed on Apr 9, 2026

Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is CA $162 per night from Apr 26 to Apr 27
CA $162
CA $180 total
Apr 26 - Apr 27
includes taxes & fees
9.2/10 Wonderful! (792 reviews)
Great location off of I-95, very clean, professional and friendly staff

Reviewed on Apr 11, 2026

Tru By Hilton Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
The price is CA $165 per night from Apr 26 to Apr 27
CA $165
CA $183 total
Apr 26 - Apr 27
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)
What a delightful surprise this place was! And the breakfast was amazing

Reviewed on Apr 11, 2026

Best Western Plus Santee Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Orangeburg County vacation package cost?
Create unforgettable memories with our Orangeburg County vacation packages, which start from a low CA $1,227. Choose the flights and hotels that suit your style. Then, add on a few sightseeing tours to cap off your unique adventure.
How do I get a cheap travel package to Orangeburg County?
You'll save big if you combine your hotels, car rentals and flights into an Orangeburg County vacation package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer over 550 air carriers and 1,000,000 properties all over the world, which means you'll always have plenty of options to choose from. Like to save even more? Add some popular activities to your package deal to unlock even bigger bargains! After all, travel is about more than just getting to your destination.
What are the top hotels in Orangeburg County?
Take a look at Baymont by Wyndham Santee and Tru by Hilton Orangeburg. They're the first choice for many travelers to Santee. If Orangeburg features on your itinerary, Fairfield Inn & Suites by Marriott Santee and Best Western Plus Santee Inn are two welcoming options.
How far in advance should I book my Orangeburg County vacation?
It can be difficult to know when is the ideal time to book your Orangeburg County vacation. But typically the earlier you book, the better the prices. In some cases, you can book your flights and hotels up to a year before your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable bargains featured on Expedia all the time.
What does an Expedia Orangeburg County travel package include?
It comes down to what you're looking for. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the entire family to Orangeburg County? A travel package that includes flights, hotels and rental cars might be a better fit. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking an Orangeburg County travel package?
When you book your flights, hotels and car rentals together, you'll walk away with great discounts. Whether you're organizing a mountain getaway in a cabin or want to stay in a ritzy city hotel, Expedia will help make it happen.
Can I choose my airline with an Orangeburg County Expedia vacation package?
With a vacation package, you're the boss. Whether you're eager to fly to Orangeburg County in coach or first class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Orangeburg County vacation package?
You sure can, and we'll help you every step of the way. You may be able to cancel or amend your Orangeburg County vacation package for free if you booked in the last 24 hours. However, you may incur a fee from your hotel, airline or car rental company for older bookings. If life throws you a curveball, have a look at our Customer Service Portal for further information.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.