Orangeburg County Vacation Packages

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Your Orangeburg County Vacation

Reserve a vacation package to Orangeburg County and make planning your getaway quick and easy. With all the logistics organized before you leave, you can focus on enjoying every second in this interesting destination. With so much to do and see on a trip to Orangeburg County, it can be difficult to know where to start. Kick off your journey in Santee at Santee State Park and Santee Cooper Country Club — two much-loved attractions here. Another great city worth adding to your itinerary is Orangeburg. Be sure not to miss Edisto Memorial Gardens and Smith-Hammond-Middleton Memorial Centre. Whether you plan to travel for a couple of days or a couple of weeks, Expedia are here to help you customize your next Orangeburg County vacation.

Top Orangeburg County Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Water's Edge Inn - Adults Only

Water's Edge Inn - Adults Only

CA $1,250
per person
Oct 28 - Nov 2
found 1 day ago
Roundtrip flight included
Detroit (DTT) to Charleston (CHS)
9.6/10 Exceptional! (490 reviews)
The stay was amazing here. We had a short stay but surely we would do this again. Would recommend to anyone. Staff is super friendly, area is perfect, perfect room size and bathroom size, etc.

Reviewed on Aug 25, 2026

The Ryder Hotel

The Ryder Hotel

Charleston Historic District
CA $1,457
per person
Oct 28 - Nov 2
found 1 day ago
Roundtrip flight included
Detroit (DTT) to Charleston (CHS)
8.8/10 Excellent! (1,150 reviews)
The Nicholas

The Nicholas

Downtown Charleston
CA $2,343
per person
Oct 8 - Oct 12
found 6 hours ago
Roundtrip non-stop flight included
Toronto (YTO) to Charleston (CHS)
9.4/10 Exceptional! (38 reviews)
The room was over $500 a night. For that we found the following: 1. The air conditioner split in the wall was filthy. Black sooty gunk right where the air comes out. 2. The toilet paper holder was falling off the wall so we used the spare loose roll that was on a table. 3. Not enough hooks in the bath so we pulled in a small side table to hold the towels. 4. The charger system did not work that was on a table. 5. There was NO ROD TO HANG CLOTHES. For over $500 a night. There was an old crooked armoire with shelves and loose hangers lying flat on a shelf. I hung my clothing outside the armoire hanging off it's crown molding. 6.The continental breakfast was not maintained or manned. 7. There was no milk for coffee. 8. Several bike locks were broken. 9. One bike had a flat tire that I discovered half a block away. 10. The bike my husband used squeaked so badly that we bought a can of WD40 in town to use on the bike. 11. Finally, a sad, pathetic small horrible and weird fake painting over the fireplace. Great location, clean sheets, completely and utterly run-down. Would never ever recommend it.

Reviewed on May 21, 2026

The Charleston Place

The Charleston Place

Charleston Historic District
CA $2,689
per person
Oct 22 - Oct 25
found 18 hours ago
Roundtrip non-stop flight included
Detroit (DTT) to Charleston (CHS)
9.6/10 Exceptional! (1,014 reviews)
Planters Inn

Planters Inn

Charleston Historic District
CA $1,970
per person
Sep 26 - Sep 30
found 17 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Charleston (CHS)
9.6/10 Exceptional! (1,002 reviews)
Great location! Very clean! Friendly staff! Beautiful room

Reviewed on Aug 22, 2026

Orangeburg County Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
CA $104
CA $115 total
Aug 30 - Aug 31
includes taxes & fees
8/10 Very good! (1,481 reviews)
"The room was clean but dated. The door was loose and had visible damage that it had been kicked in and not replaced. The staff was great. It was a last-minute choice as my husband got sick while driving back home."

Reviewed on Aug 27, 2026

Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
CA $135
CA $150 total
Sep 13 - Sep 14
includes taxes & fees
Tru By Hilton Santee
Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

3608 Saint Matthews Rd Orangeburg SC
Fully refundableReserve now, pay when you stay
CA $80
CA $88 total
Sep 2 - Sep 3
includes taxes & fees
Super 8 by Wyndham, Orangeburg
See all 692 properties in Orangeburg County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Orangeburg County vacation package cost?
Create unforgettable memories with our Orangeburg County vacation packages, which start from a low CA $1,250. Choose the flights and hotels that suit your style. Then, add on a few sightseeing tours to cap off your unique adventure.
How do I get a cheap travel package to Orangeburg County?
You'll save big if you combine your hotels, car rentals and flights into an Orangeburg County vacation package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer over 550 air carriers and 1,000,000 properties all over the world, which means you'll always have plenty of options to choose from. Like to save even more? Add some popular activities to your package deal to unlock even bigger bargains! After all, travel is about more than just getting to your destination.
What are the top hotels in Orangeburg County?
Take a look at Baymont by Wyndham Santee and Tru by Hilton Orangeburg. They're the first choice for many travelers to Santee. If Orangeburg features on your itinerary, Fairfield Inn & Suites by Marriott Santee and Best Western Plus Santee Inn are two welcoming options.
How far in advance should I book my Orangeburg County vacation?
It can be difficult to know when is the ideal time to book your Orangeburg County vacation. But typically the earlier you book, the better the prices. In some cases, you can book your flights and hotels up to a year before your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable bargains featured on Expedia all the time.
What does an Expedia Orangeburg County travel package include?
It comes down to what you're looking for. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the entire family to Orangeburg County? A travel package that includes flights, hotels and rental cars might be a better fit. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking an Orangeburg County travel package?
When you book your flights, hotels and car rentals together, you'll walk away with great discounts. Whether you're organizing a mountain getaway in a cabin or want to stay in a ritzy city hotel, Expedia will help make it happen.
Can I choose my airline with an Orangeburg County Expedia vacation package?
With a vacation package, you're the boss. Whether you're eager to fly to Orangeburg County in coach or first class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Orangeburg County vacation package?
You sure can, and we'll help you every step of the way. You may be able to cancel or amend your Orangeburg County vacation package for free if you booked in the last 24 hours. However, you may incur a fee from your hotel, airline or car rental company for older bookings. If life throws you a curveball, have a look at our Customer Service Portal for further information.

Stay near popular Orangeburg County attractions

Santee State Park

8.0/10 (219 reviews)
You can take time to visit Santee State Park during your travels to Santee. While you're here, you can savor the top-notch restaurants.
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Santee Cooper Country Club

7.8/10 (94 reviews)
Enjoy a round of golf in Santee at Santee Cooper Country Club. While you're here, you can savor the top-notch restaurants.
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Edisto Memorial Gardens

8.8/10 (110 reviews)
Explore the great outdoors at Edisto Memorial Gardens, a lovely green space in Orangeburg. While you're here, you can savor the top-notch restaurants.
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Santee National Golf Club

8.0/10 (74 reviews)
Enjoy a round of golf in Santee at Santee National Golf Club. While you're here, you can savor the top-notch restaurants.
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Smith-Hammond-Middleton Memorial Center

8.2/10 (36 reviews)
Catch an event at Smith-Hammond-Middleton Memorial Center during your trip to Orangeburg. While you're here, you can savor the top-notch restaurants.
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Santee Town Hall

Santee Town Hall is just one of the places to see in Santee, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.